Dissolution Testing/Content Uniformity
In vitro dissolution testing serves as an important tool for characterizing the biopharmaceutical quality of a product at different stages in its life cycle. In early drug development, characterization of in vitro dissolution properties is essential for identifying alternative formulation candidates for further development and for evaluation of active ingredients or drug substances.
The Nanostream CL System is ideally suited to rapidly analyze multiple replicates or samples drawn at multiple time points. The Nanostream CL System allows you to capture more data points per sample than conventional LC instrumentation.
Samples from multiple time points can be analyzed simultaneously to rapidly generate dissolution profiles, such as the one shown here for acetaminophen in a pH 5.8 bath.